Are you familiar with Neu5Gc and its proinflammatory role? I'm sure, most you have heard the term "chronic inflammation" and maybe suffer or know someone who suffer from an inflammatory disease. Neu5Gc or N-glycolylneuraminic acid is the nonhuman sialic acid. Humans cannot synthesize Neu5Gc because the human gene CMAH is irreversibly mutated. Sialic acids have never been detected in plants and are found in large amounts in foods of mammalian origin, especially in red meats